Internal server error 500, hosting Node.js Express 4 application template from Visual Studio 2017 in Azure

I create a project from the project template: "Basic Azure Node.js Express 4 Application" in Visual Studio 2017 Enterprise edition.

When I run it locally it works fine. Now I publish this to Azure using the below Publish menu:

I get the following error:

iisnode encountered an error when processing the request.

HRESULT: 0x2
HTTP status: 500
HTTP subStatus: 1001
HTTP reason: Internal Server Error

I'm making no changes to the code from the template.

Any Ideas?

via Aram