Develop Angular2 with Node.js inside of a .Net Web App Project?

Can I use Node.js to develop an app inside of a .Net web application (not .Net Core)?

I need the .Net Web App for simple deployment to an IIS server, communicating with a SQL Server, Windows Authentication and writing some web services. Still, I would like to write the front-end using Angular2 but the best practice seems to be developing it for a Node.js server.

Visual Studio 2017 has built-in TypeScript compilation so it seems I should be able to develop Angular2 without Node but there doesn't seem to be any examples of this.

Would it be possible to develop the Angular2 app inside of my .Net project but go to production without Node.js?

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